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Cellular Dynamics.jpg

Cellular Dynamics公司可以大规模从干细胞诱导分化生产人类细胞,用于基础研究,药物发现和再生医学应用。CDI提供了几种末分化的细胞种类作为目录产品:iCell心肌细胞,iCell神经元,iCell内皮细胞和iCell肝细胞。 CDI的MyCell®产品组合能够为客户提供的供体样品进行重编程,基因编辑和分化。该公司还有几种来源于多能干细胞的原型产品,包括iCell心脏祖细胞,iCell造血祖细胞,iCell星形胶质细胞和iCell骨骼成肌细胞等。

 

Fujifilm, once a Company whose core business was photographic film, has diversified and strengthened its portfolio based on developing or acquiring proprietary technologies as well as a deeply held corporate philosophy of enhancing the quality of human lives worldwide. One key area of focus for the Company is Healthcare, and Fujifilm acquired Cellular Dynamics International in May 2015, renamed it to FUJIFILM Cellular Dynamics, Inc.(FCDI) in 2018 to drive innovation in this business area. We see great potential in FCDI as a key component in our mission to be the global leader in regenerative medicine and drug discovery through cutting-edge science and technology.

 

To date FCDI has already achieved leadership in the induced pluripotent stem cell (iPSC) field as one of the only companies in the world to industrially manufacture human cells derived from iPSCs with high quality, purity, and reproducibility and in virtually unlimited quantities. Not only have we achieved this across multiple healthy and diseased donors for the research market but also, we have begun to manufacture human cells under cGMP conditions – a requirement as these human cellular products move from a tool used in drug discovery into a therapy used in regenerative medicine applications.

 

Cellular Dynamics公司的主要产品包括:

iCell Cardiomyocytes

iCell Cardiac Progenitor Cells

iCell Neurons

iCell Astrocytes

iCell DopaNeurons

iCell Hepatocytes 2.0

iCell Hepatoblasts

iCell Skeletal Myoblasts

iCell Endothelial Cells

iCell Hematopoietic Progenitor Cells

iCell Macrophages

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Allele Biotechnology.jpg

Allele Biotechnology位于美国圣地亚哥市,主要专注于对生物过程的机制进行探索,以开发生物医学及治疗相关的技术和产品。以各个物种的iPS细胞、人类cGMP iPS细胞及衍生的细胞为材料,Allele Biotechnology利用专利性的非整合细胞编辑方法,开发了出了细胞治疗和药物筛选的技术。Allele Biotechnology具有深厚的基因组修饰和细胞荧光报告因子的经验,为客户提供优异的细胞检测解决方案。Allele Biotechnology还提供荧光蛋白、高效荧光素酶底物、基因分型试剂盒、骆驼抗体等产品;此外还在RNA干扰领域尤其独特的专利。

 

Allele Biotechnology and Pharmaceuticals, Inc. is a private, San Diego-based company that explores the mechanisms of biological processes to develop technologies and products for biomedical research and therapy development.

 

Our mission is to increase accessibility to innovative molecular biology research tools by offering cutting edge technologies in individual products and fully integrated platforms. Allele utilizes proprietary non-integrating cellular reprogramming methods to develop cell therapy and enable drug discovery through the use of human and non-human primate iPS cells, cGMP-grade human iPS cells and their derivatives. With additional expertise in genome modification and unique cell-based fluorescence sensors/reporters, Allele provides advanced cell and assay development solutions. Allele also has developed a wide variety of advanced research tools including superior fluorescent proteins, highly efficient luciferase assay substrates, genotyping kits, and camelid antibodies that have been validated for co-immunoprecipitation, histology, and flow cytometry. The Company has also been a leader in the RNAi field with its patents in Pol III promoter-driven siRNA, shRNA, and miRNA.

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